Metabolic adaptation of Mycobacterium tuberculosis (M.tuberculosis) to microbicidal intracellular environment of host macrophages is fundamental to its pathogenicity.However, an in-depth understanding of metabolic adjustments through key reaction pathways and networks is limited.To understand how such changes occur, we measured the cellular metabol
The body of literature on the integration of Christianity and psychology and/or counseling indicates that integration is best learned and taught through spiritual formation and mentoring relationships.More specifically, the ongoing spiritual formation of counseling or psychology faculty in Christian, integrative programs and their ability to mentor
The human 8-oxoguanine DNA glycosylase OGG1 is xbox series x yoke involved in base excision repair (BER), one of several DNA repair mechanisms that may counteract the effects of chemo- and radiation therapy for the treatment of cancer.We envisage that potent inhibitors of OGG1 may be found among the 9-alkyl-8-oxoguanines.Thus we explored synthetic
Phenol and Cr(VI) are two of the most common organic and heavy metal-based pollutants found in industrial effluents.Both pollutants pose considerable health risks if left untreated.Activated carbon adsorption is generally used for the physical removal of these types case of whispering angel of pollutants during wastewater treatment.This work invest
Summary: Early phase dose-finding (EPDF) trials are key in the development of novel therapies, with their findings directly informing subsequent clinical development phases and providing valuable insights for reverse translation.Comprehensive and transparent reporting of these studies is critical for their accurate and critical interpretation, whic